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Best Southwest American Restaurants in San Antonio

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71 restaurants available nearby

A photo of Supper restaurant
1. Supper
4.6
Exceptional(3182)
Price: Expensive
• Mexican • Downtown
Booked 48 times today
Supper, nestled in the heart of Downtown San Antonio, is a shining beacon of exquisite American cuisine. Housed within the historic Hotel Emma, this restaurant seamlessly marries South Texas hospitality with a modern flair. Diners frequently rave about the "sensational" food and "wonderful atmosphere," making it a favored spot for both locals and visitors alike. Whether enjoying a brunch with friends or a romantic dinner overlooking the river, Supper offers a diverse menu that guarantees satisfaction. The "divine" dishes and "attentive" service ensure that every meal is a memorable experience, solidifying Supper as a must-visit destination for authentic American dining.
A photo of Southerleigh Fine Food & Brewery restaurant
2. Southerleigh Fine Food & Brewery
4.8
Exceptional(3117)
Price: Moderate
• Mexican • Downtown
Booked 60 times today
Southerleigh Fine Food & Brewery in Downtown San Antonio stands as a beacon of authentic American cuisine, blending coastal classics with comforting Southern flavors. Helmed by the talented Chef Jeff Balfour, the restaurant offers a dynamic, seasonally shifting menu that showcases his innovative craftsmanship. Diners rave about the "fantastic food," with standout dishes like the perfectly fried Snapper Throats and "best fried chicken in San Antonio." The brewery enhances the dining experience with its custom-crafted beers. Guests consistently praise the "outstanding service" and inviting atmosphere, making it a must-visit for anyone seeking a true taste of American culinary excellence.
A photo of Chart House Restaurant - Tower of the Americas restaurant
3. Chart House Restaurant - Tower of the Americas
4.4
Awesome(16656)
Price: Moderate
• Mexican • Downtown
Booked 188 times today
Chart House Restaurant - Tower of the Americas in Downtown San Antonio offers an exquisite American dining experience. Renowned for serving up fresh seafood and succulent steaks, the restaurant has been praised for its "absolutely fantastic" cuisine and service that goes "above and beyond." Guests rave about the cedar plank salmon and prime rib, describing their meals as "delicious" and "top tier." The stunning panoramic views from 750 feet in the air make dining here unforgettable. With a rich heritage of over 50 years, Chart House continues to redefine authentic American cuisine, making it a must-visit for both locals and visitors.
A photo of Domingo Restaurante restaurant
4. Domingo Restaurante
4.5
Awesome(818)
Price: Expensive
• Mexican • Downtown
Booked 61 times today
Join us in our open-air restaurant on the Historic San Antonio River Walk with a natural ambiance where curated contemporary art intersects with a historical setting. Domingo's menus offer the flavors of South Texas and an agave-forward beverage program celebrating the culture of San Antonio with modern culinary flair.
A photo of Bohanan's Prime Steaks and Seafood restaurant
5. Bohanan's Prime Steaks and Seafood
4.8
Exceptional(8293)
Price: Very Expensive
• Mexican • Downtown
Booked 48 times today
Bohanan's Prime Steaks and Seafood in downtown San Antonio elevates seafood dining to an art form. Known for its "succulent seafood flown in fresh daily," the restaurant ensures that each dish bursts with authentic, ocean-fresh flavors. Diners rave about the "macadamia encrusted red snapper" and "outstanding salmon" that epitomize the exquisite quality of their seafood offerings. The AAA Four Diamond-rated restaurant pairs its seafood with impeccable service, creating an extraordinary dining experience. Located in a historic building near the River Walk, Bohanan's is a must-visit for seafood lovers seeking a memorable meal in a stunning, elegant setting.
A photo of Mezquite restaurant
6. Mezquite
4.6
Exceptional(203)
Price: Moderate
• Mexican • Downtown
Booked 49 times today
Mezquite in Downtown San Antonio is a shining example of authentic Farm-to-table cuisine, celebrating the rich food pathways of the Sonoran region. This vibrant restaurant delights diners with expertly grilled meats and homemade flour tortillas. As one glowing review highlighted, "The food was some of the best Mexican food we have had and we are native to San Antonio." The dedication to fresh, quality ingredients is evident in every dish, from the savory elotes to the mouthwatering carne asada. With an inviting atmosphere and a menu full of savory delights, Mezquite promises an unforgettable dining experience perfect for any occasion.
A photo of Isidore restaurant
7. Isidore
4.6
Exceptional(98)
Price: Very Expensive
• Mexican • Downtown
Booked 31 times today
Isidore, nestled in the heart of Downtown San Antonio, offers a remarkable journey into the world of Contemporary American cuisine. This vibrant eatery is celebrated for its "fantastic farm to market experience," showcasing the finest local Texas ingredients with a creative twist. The ever-changing menu ensures that each visit is a new adventure, with standout dishes like the "embered beets" and "Wagyu Ribeye" receiving rave reviews. Isidore's open kitchen concept adds a dash of theatrical flair to dining, while the robust wine list expertly curated by their sommelier perfectly complements each dish. This is a must-visit for those seeking an authentic and innovative dining experience.
A photo of Boiler House at Pearl restaurant
8. Boiler House at Pearl
4.6
Exceptional(2110)
Price: Expensive
• Mexican • Downtown
Booked 40 times today
Boiler House at Pearl is a standout destination for authentic American cuisine in Downtown San Antonio. Nestled in the historic Pearl Brewery complex along the vibrant River Walk, this restaurant offers a unique dining experience with a focus on "Texas ranch-style" dishes that capture the essence of American flavors. Led by Executive Chef Alberto "Beto" Gutierrez, the menu boasts high-quality, locally-sourced grilled items that are consistently praised by diners. Reviewers rave about the "amazing experience" and "delicious food," with standout dishes like the perfectly cooked porterhouse steak and the inventive shrimp fritto misto. The warm, welcoming atmosphere and attentive service make Boiler House a must-visit.
A photo of Seasons 52 - San Antonio restaurant
9. Seasons 52 - San Antonio
4.8
Exceptional(717)
Price: Expensive
• Mexican • Alamo Heights
Booked 58 times today
Seasons 52 in Alamo Heights, San Antonio, is renowned for its exquisite Seafood cuisine, where freshness and flavor are at the core of every dish. Diners rave about the "outstanding meal" experiences, with specialties like the Chilean sea bass leaving a lasting impression. The restaurant’s menu is crafted with seasonal ingredients, ensuring that each Seafood offering is at its peak of quality and taste. Guests appreciate the "great fresh food" and the attention to detail in preparation, which is evident in every bite. With a commitment to providing lighter, naturally flavorful options, Seasons 52 stands out as a top choice for Seafood lovers.
A photo of Brenner's on the River Walk restaurant
10. Brenner's on the River Walk
4.6
Exceptional(345)
Price: Moderate
• Mexican • Downtown
Booked 32 times today
Brenner's on the River Walk in San Antonio offers a quintessential American dining experience that beautifully marries tradition with elegance. With roots tracing back to 1936, Brenner's is renowned for its commitment to authentic American flavors and exceptional quality. Guests rave about its "phenomenal" dishes, especially the American Wagyu and the delectable bacon-wrapped shrimp. The restaurant's picturesque setting along the River Walk adds to its charm, providing breathtaking views from both indoor and balcony seating. Patrons consistently highlight the "excellent" service, noting that it enhances their dining experience, making Brenner's a must-visit for anyone seeking top-tier American cuisine.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

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