Best Southern American Restaurants in Mission District

139 restaurants available nearby

1. Curio

4.3

Price: Moderate

• Southern american • Mission District

Booked 19 times today

Located in the vibrant Mission District of San Francisco, Curio offers a delightful haven for Comfort Food enthusiasts. Praised for its "sneaky good" regional American cuisine, Curio stands out with its fried chicken and waffle bites acclaimed as "excellent" and the "best hamburger I've had in a long time!" The restaurant's ambiance, enhanced by live music and unique decor inspired by its history as a mortuary, adds an eclectic charm to the dining experience. Whether it's the hearty brunch options or the comforting evening meals, guests consistently celebrate the generous portions and the quality of the dishes. With glowing reviews like "Food was really good. Service was excellent," Curio is indeed a gem for those seeking authentic and satisfying Comfort Food in a lively, inviting setting.

A photo of House of Prime Rib restaurant

2. House of Prime Rib

4.8

Exceptional(15835)

Price: Very Expensive

• Southern american • Civic Center / Hayes Valley / Van Ness

Booked 246 times today

House of Prime Rib, nestled in the vibrant Civic Center / Hayes Valley / Van Ness neighborhood of San Francisco, is a bastion of exceptional American cuisine, specializing in an unparalleled prime rib experience. Celebrated for its 62-year legacy, this restaurant is a favorite for its "juicy and perfectly cooked" prime rib selections, from the English Cut to the King Henry Cut. Patrons rave about the "tender and flavorful" meat and the classic accompaniments like creamed spinach and Yorkshire pudding, emphasizing that it's not just a meal but an "unforgettable experience." The ambiance, described as energetic and celebratory, perfectly complements the top-notch service and old-school charm, making House of Prime Rib a must-visit for anyone seeking the quintessential American dining experience.

A photo of Tartine Manufactory - San Francisco restaurant

3. Tartine Manufactory - San Francisco

4.6

Exceptional(1029)

Price: Expensive

• Southern american • Mission District

Booked 23 times today

Tartine Manufactory in San Francisco's vibrant Mission District is hailed as a haven for pizza aficionados, offering a delightful culinary experience with its world-class sourdough pizzas. Renowned for its market-driven menu that showcases the artisanal bread-making prowess of Chad Robertson, the restaurant earns rave reviews for its unique offerings. Guests consistently praise the "delicious" and "creative" pizza options, like the seasonal corn pizza which has been described as "spectacular." The inviting atmosphere complements the exceptional food, with one review noting, "The service, environment, and food were incredible." Whether it's the cacio e pepe pizza enhanced with fresh arugula or the burrata peach salad, each dish is crafted with the utmost care, making Tartine Manufactory a must-visit for those seeking authentic and high-quality Pizzeria cuisine in San Francisco.

4. Frances

4.9

Exceptional(3657)

Price: Very Expensive

• Southern american • The Castro

Booked 20 times today

Frances, nestled in the vibrant Castro neighborhood of San Francisco, is a contemporary American gem where culinary creativity shines. Chef Melissa Perello presents a menu that epitomizes modern California cuisine, focusing on fresh, local ingredients sourced from neighboring markets, farms, and producers. The restaurant, named after Perello’s grandmother, encapsulates a fusion of refined yet comfortable sensibilities in both its food and decor. Guests rave about dishes like "the best gnocchi we’ve had anywhere" and the "flawlessly cooked" pork chop. With reviews praising its "creative dishes and wonderful wine pairings," Frances stands out as a top destination for those seeking a stellar dining experience. The ambiance is described as "cozy and elegant," making it perfect for any occasion, from casual dinners to special celebrations.

5. Fable - SF

4.7

Exceptional(2187)

Price: Moderate

• Southern american • The Castro

Booked 36 times today

Nestled in the vibrant Castro neighborhood of San Francisco, Fable - SF epitomizes the spirit of Californian cuisine with its fresh, seasonal offerings and a delightful garden patio setting. Recognized for serving "the best brunch in town," this charming spot impresses with its innovative dishes that showcase California's rich produce. Patrons rave about the experience, noting the "beautiful, sunny SF patio" and "spectacular food and drinks." With glowing reviews like "the food is always good and the service too…there is nothing quite like sitting in the back patio," Fable - SF stands out as a quintessential destination for those seeking authentic and high-quality Californian dining in a picturesque outdoor setting.

A photo of State Bird Provisions restaurant

6. State Bird Provisions

4.7

Exceptional(3241)

Price: Very Expensive

• Southern american • Western Addition

Booked 74 times today

State Bird Provisions in San Francisco's Western Addition neighborhood offers a truly American dining experience that captures both the spirit and innovation of contemporary American cuisine. Renowned for its unique approach, the restaurant features a dim sum-style service that delivers a parade of creative and seasonal dishes, earning high praise from diners. Guests rave about the "extraordinary place with extraordinarily good food" and the "interesting, seasonal, and well-balanced flavors." The energy and creativity of the menu make every visit a delightful adventure, with standouts like the duck liver mousse and the smoked trout dip. The combination of top-notch service and a lively atmosphere ensures a memorable dining experience that epitomizes the best of American culinary excellence. This gem is a proud testament to the rich, evolving food scene of San Francisco.

7. The Progress

4.8

Exceptional(2467)

Price: Very Expensive

• Southern american • Western Addition

Booked 61 times today

The Progress, located in San Francisco's vibrant Western Addition, is a beacon of Contemporary American cuisine, celebrated for its innovative and locally-sourced dishes. Guests frequently rave about the "beyond amazing" duck and the inventive flavor combinations that make each visit a culinary adventure. With its reputation for "exceptional food and impeccable service," The Progress offers a dynamic dining experience, described by many as "the greatest dinner party ever." It's not just the food that impresses; the cocktails are crafted with creativity, leading one guest to proclaim, "My wife had one of the most creative and delicious drinks she had ever had." Whether it's the warmly recommended small plates or the standout duck, The Progress ensures a memorable and delightful meal with every visit, making it a must-visit destination for anyone seeking the best of Contemporary American dining in San Francisco.

8. Mr. Digby's

4.6

Exceptional(464)

Price: Expensive

• Southern american • Noe Valley

Booked 16 times today

At Mr. Digby's in Noe Valley, San Francisco, diners are treated to a delectable array of elevated American comfort food that has earned it rave reviews and the title of "Best Food of the Week" by the Chronicle in 2021. Guests consistently praise dishes like the "consistently great" chicken pot pie and the "best meatloaf" in the area, highlighting the quality and authenticity of the cuisine. With a cozy yet polished setting, Mr. Digby’s offers an inviting atmosphere perfect for enjoying classic comfort dishes. As one diner put it, the experience is "always above average," with food and service that make you wish you "lived closer." Whether it’s the perfectly seasoned mussels or the rich, creamy meatloaf, Mr. Digby’s stands out as a gem for comfort food lovers.

A photo of The Rotunda at Neiman Marcus - San Francisco restaurant

9. The Rotunda at Neiman Marcus - San Francisco

4.8

Exceptional(6098)

Price: Expensive

• Southern american • Downtown / Union Square

Booked 105 times today

The Rotunda at Neiman Marcus in San Francisco's Union Square is a quintessential destination for those seeking an exceptional American dining experience. Known for its elegant ambiance and meticulous service, The Rotunda offers a luxurious afternoon tea service that has won the hearts of locals and tourists alike. Patrons rave about the "delicious assortment of food" and "excellent ambience," highlighting the restaurant's ability to deliver a top-tier culinary experience. From the superb seafood selections like the praised shrimp and crab Louie salad to the classic American burger, every dish is crafted with excellence. Guests continually commend the Rotunda for its "outstanding service" and "beautiful setting," making it a must-visit for anyone looking to indulge in the finest American cuisine in a stunning, historic venue.

A photo of Firefly Restaurant restaurant

10. Firefly Restaurant

4.9

Exceptional(3004)

Price: Expensive

• Southern american • Noe Valley

Booked 33 times today

Discover the heart of American cuisine at Firefly Restaurant in Noe Valley, San Francisco, where every dish tells a story of tradition and creativity. Renowned for its ever-evolving seasonal menu, Firefly stands out as a beacon of culinary excellence. Patrons often describe their dining experience as unforgettable, with one diner noting, "the fried chicken was excellent," while another praised the "food cooked to perfection." The restaurant's dedication to accommodating diverse dietary needs, such as vegan and gluten-free options, further showcases its commitment to all diners. Firefly's vibrant atmosphere and thoughtful service make it a cherished gem in the community, where both the food and the warm, inviting ambiance bring people back time and again. Whether it's the "sublime" trout or the "ambrosial" furikake-crusted trout, each meal is a celebration of authentic American flavors, lovingly prepared and served.

‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you

J
JessicaVIP
Los Angeles •5 reviews
5.0
Dined 3 days ago
The food and service were excellent! The pork chop is an absolute must. Drinks were very creative and paired very well with the food. The decor, lighting, and mood inside were very mid century inspired, making for a fun dining experience. We will definitely be coming back!
More info
PreludePrice: Expensive• Californian• Financial District / Embarcadero
•
4.6
B
BVIP
San Francisco Bay Area •132 reviews
5.0
Dined 3 days ago
We ordered drinks, which came promptly and were good. Both of us had jambalaya. It was quite tasty. The show started somewhat late, so we had time for another round of drinks. Once the show started, and during and after the show, service was less available. It took us a bit of time to get our check, but we were able to chat with the performers, so it was fun. The parking discount at the Mason-Ellis garage worked out well. We highly recommend Biscuits and Blues for dinner and a show! We'll definitely be back.
More info
Biscuits and BluesPrice: Expensive• Southern• Downtown / Union Square
•
4.7
J
J. Alan
San Francisco Bay Area •2 reviews
5.0
Dined 5 days ago
The server Jake was great. We ate at the Dog Patch location (last day open) The food was exceptional. I am looking forward to visiting the Clement location in the future. All the best to the owners and staff at Hard Knox. Merry Christmas. Thank you!
More info
Hard Knox Cafe on Clement StreetPrice: Moderate• Southern• Richmond District
•
4.8
C
ChadVIP
San Francisco Bay Area •7 reviews
5.0
Dined on Nov 7, 2024
Excellent food! Highly recommended. Looking forward to going back.
More info
Hard Knox Cafe on 3rd StreetPrice: Moderate• Southern• Potrero Hill / Dogpatch
•
4.6

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Mission District

Southern american

Best Southern American Restaurants in Mission District

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139 restaurants available nearby

1. Curio

2. House of Prime Rib

3. Tartine Manufactory - San Francisco

4. Frances

5. Fable - SF

6. State Bird Provisions

7. The Progress

8. Mr. Digby's

9. The Rotunda at Neiman Marcus - San Francisco

10. Firefly Restaurant

See what locals rave about

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